(951) 666-0706

18821 Delaware St, Suite 105
Huntington Beach, CA



The Art of Microneedling

Microneedling is the art of penetrating the skin with very small needles creating controlled tissue damage that stimulates the body’s healing response. This procedure was documented in Chinese medical texts as early as 100 BC. It was used to allow Qi (vital energy) to enter through the channels, which were opened by needling the skin tissue. This results in increased collagen and elastin production, enhanced vascularity and, ultimately, skin rejuvenation.

Microneedling is indicated for treatment of wrinkles, pigment, melasma, photodamaged skin, acne scars or skin laxity. It is safe for use in all skin types, Fitzpatrick I-VI.


We use the FDA-approved Skin Pen, which is a precision instrument with sterile,  disposable needles. The Skin Pen safely controls the depth of the channels. The open channels facilitate absorption of the following treatments to the dermis, which is where most skin problems originate:
  • Exosomes
  • Platelet-Rich-Plasma
  • Tranexamic Acid
Microneedling skin pen

Microneedling with Exosomes

Microneedling with exosomes can lead to noticeable and significant beneficial changes in skin quality. 

We all have exosomes. They are instrumental in our day-to-day healing, repair and collagenesis. As we age, our stem cells produce less exosomes. Using exosomes from younger stem cells makes an extraordinary difference in healing.

We use high quality exosomes derived from mesenchymal embryonic cells, which are the cells that create connective tissue in our bodies. We purchase exosomes from Kimera, who is the most reputable provider of exosomes. Their Kimera Vive is specifically formulated to treat skin after microneedling. We invite you to visit their website. Also please know that Kimera(r) Labs received FDA Phase I/IIa IND Clearance for its MSC Exosomes Human study.

Microneedling with Exosomes

Exosomes are extremely small vesicles or pouches that contain a large number of products: growth factors, cell signaling components, proteins that serve many functions, messenger RNA and DNA. They ae produced by every cell and extruded from their walls to communicate with other cells: the typical “message in a bottle”.

Exosomes of mesenchymal origin transport cargo derived from mesenchymal stem cells (MSCs).  MSCs can self-renew and have the potential to differentiate into a variety of connective tissues. Their exosomes are used for orchestrating tissue repair and rejuvenation.

How does Platelet Rich Plasma compare with exosomes?

Platelet Rich Plasma or PRP is frequently used in conjunction with microneedling to enhance skin rejuvenation, treat acne scars or melasma. Platelets contain exosomes, but their exosomes are not as rich in growth factors or regenerative proteins as compared to purified mesenchymal exosomes.

What do Exosomes Do?

Exosomes wake up cells from a dormant state into action – which is why they work in alopecia (hair loss). They stimulate tissue regeneration and healing.

Exosomes cannot replicate themselves, so they cannot undergo malignant transformation. They have very low immunogenicity, and therefore, immune-mediated reactions are unlikely.

Exosomes cannot penetrate intact skin, so in order to successfully apply them, microneedling or a laser pre-treatment is needed.

In Summary:

Exosomes are more effective in tissue regeneration, healing and repair as compared to microneedling alone or microneedling with Platelet-Rich Plasma.


Microneedling is a great method to deliver Platelet Rich Plasma into skin tissue. The Platelet Rich Plasma is obtained from the patient’s own blood, and once drawn, it is centrifuged to separate the blood solid components from the serum, or platelet-rich plasma.

Platelets contain several types of growth factors that enhance the activation of tissue components to induce cell proliferation, vascular enhancements and activation of stem cell, fibroblasts, and keratinocytes. They also contain exosomes.

Microneedling with Platelet Rich Plasma may be used to:

  • Treats aging and photodamaged skin
  • Heals skin after ablative procedures used to address acne scars
  • Assists in pigment management, decreasing the inflammation associated with Melasma
  • Treats hair loss and alopecia
  • Complement laser treatments that promote collagen production


How many treatments?

We recommend at least 3 monthly treatments to achieve optimal results.

Microneedling with Platelet Rich Plasma
Melasma Laser Treatment
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